Pharmacological and Physiological Antagonism.

Topic: Issues Behind Addictive Drug Use-

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Topic: Pharmacological and Physiological Antagonism

Details: Prior to beginning work on this discussion, read the required chapters from the text and review the required articles for this week. Alcohol and caffeine have nearly opposite effects on behavior and the nervous system, yet these substances are not used to treat overdose or addiction to the other. Why not use caffeine to treat alcohol addiction? Analyze the issues of pharmacological and physiological antagonism. Explain the receptor systems involved and the central nervous system structures effects with regard to this question. Frame your analysis in terms of drug action first and other consequences second.

Details: Prior to beginning work on this discussion, read the required chapters from the text and review the required articles for this week. Humans have engaged in psychoactive drug use, sometimes in formal (ceremonial) settings and sometimes recreationally, since before recorded history. It has only been in the last century or so that abuse and addiction have become large-scale problems. Using the literature and your own insights into these issues, formulate an argument as to why the problem has reached its current scale. In your discussion, evaluate the employment of psychoactive drugs from the aspects of a risk-benefits analysis and ethical considerations such as the risk of addiction versus the cost of punitive action. Also explain purely pharmacological issues such as pharmacokinetics and routes of drug administration and dose. If needed, include factors such as supply, cultural attitudes to drug use, and the context of drug use.

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